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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2195894Generated: October 27, 2026

1-(2-Bromoethyl)-4-chlorobenzene → 5-(4-chlorophenethyl)-6-chloro-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indole

https://huagongshe.com/reaction/2195894

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Bromoethyl)-4-chlorobenzeneHCID 23029—
Reactant1-Methyl-4-piperidoneHCID 74049—
Reactant2-Chlorophenylhydrazine hydrochlorideHCID 443287—
SolventTriethylamineHCID 8471—
Product5-(4-chlorophenethyl)-6-chloro-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indoleHCID 57876171—

Reaction Steps

The title compound is prepared by following Method 8 by using 1-(2-bromoethyl)-4-chlorobenzene, 2-chlorophenylhydrazine hydrochloride, triethylamine and N-methyl-4-piperidone

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08338408B2
Source datasetuspto-grants-2012_12
ORD IDord-d2f91437a47649829fa4480dd057a87f
Source noteuspto-grants-2012_12