HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1) → 8-chloro-2,3,4,5-tetrahydro-2-methyl-5-(3-(pyrrolidin-1-yl)propyl)-1H-pyrido[4,3-b]indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1) | HCID 71600 | — |
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Reactant | 1-(3-Bromopropyl)pyrrolidine | HCID 13034044 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 8-chloro-2,3,4,5-tetrahydro-2-methyl-5-(3-(pyrrolidin-1-yl)propyl)-1H-pyrido[4,3-b]indole | HCID 57875948 | — |
Reaction Steps
The title compound is prepared by following Method 8 by using 1-(3-bromopropyl)pyrrolidine, 4-chlorophenylhydrazine hydrochloride, triethylamine and N-methyl-4-piperidone
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338408B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-7794b7b6bd8145df94cf2c73011faaae |
| Source note | uspto-grants-2012_12 |