Ethanol → N-{4-[4-(Diethylcarbamoyl-phenyl-methyl)-piperazin-1-yl]-3-fluoro-phenyl}-2-pyridin-3-yl-benzamide maleate salt

Participants

Reaction Steps

In a 100 mL flask charged with absolute ethanol (20 mL) ethanol was added N-{4-[4-(diethylcarbamoyl-phenyl-methyl)-piperazin-1-yl]-3-fluoro-phenyl}-2-pyridin-3-yl-benzamide (273.7 mg, 0.48 mmol). Sonication and addition of CH2Cl2 (4 mL) yielded a homogeneous solution. Maleic acid (62.6 mg) was then added in one portion and the resulting mixture stirred for 3 h. The solvents were removed with the rotary evaporator to yield an off-white foam. The foam was dried under vacuum to yield the title compound as an off-white foam.

Provenance & Evidence