Benzene, (5-iodopentyl)- → 3-tert-butyl-2-methyl-4-phenyl-6-[(5-phenylpentyl)oxy]isoquinolin-1(2H)-one

HRID 2196391Notes

Reaction equation

HRID 2196391 reaction equation
[C:1]([C:5]1[N:6]([CH3:33])[C:7](=[O:32])[C:8]2[C:13]([C:14]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:12][C:11]([O:21][CH2:22][CH2:23][CH2:24][CH2:25]C1C=CC=CC=1)=[CH:10][CH:9]=2)([CH3:4])([CH3:3])[CH3:2].[C:34]1([CH2:40]CCCCI)[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1>>[C:1]([C:5]1[N:6]([CH3:33])[C:7](=[O:32])[C:8]2[C:13]([C:14]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:12][C:11]([O:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:40][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)=[CH:10][CH:9]=2)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 561241Benzene, (5-iodopentyl)-HCID 113166023-tert-butyl-2-methyl-4-phenyl-6-(4-phenylbutoxy)isoquinolin-1(2H)-one

Product 1

HCID 117753733-tert-butyl-2-methyl-4-phenyl-6-[(5-phenylpentyl)oxy]isoquinolin-1(2H)-one

Procedure

Following the procedure for 3-tert-butyl-2-methyl-4-phenyl-6-(4-phenylbutoxy)isoquinolin-1(2H)-one, using 5-phenyl-1-iodopentane in place of 4-phenyl-1-iodobutane, the titled compound was obtained.

Sources & evidence

ORD record
ord-71904e38573e4961b3f9386c1c297704
Source dataset
uspto-grants-2012_12
Patent number
US08338449B2

Reaction notes

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