HCID 68508262, compound → HCID 11255286, compound

Participants

Reaction Steps

tert-butyl 2-(6-methoxy-3-methyl-1-oxo-4-phenylisoquinolin-2(1H)-yl)ethylcarbamate (800 mg) was dissolved in 200 mL EtOAc and cooled to 0 C. HCl gas was bubbled through the solution for 5 min, and the reaction was warmed to room temp. After stirring for 4 h, the reaction was filtered to isolate the hydrochloride salt of the title compound as a white solid.

Provenance & Evidence