Borane → HCID 69299659, compound

Participants

Reaction Steps

To a stirred suspension of 30 (317 mg, 0.966 mmol) in THF (966 μl) at 0° C. was added a solution of BH3.THF (1M in THF) (3.9 mL, 3.9 mmol). The resulting solution was allowed to stir for 4 h at room temperature. Then more borane.THF (1M in THF) (1 mL) was added. Stirring was continued for 16 h at room temperature. The mixture was quenched with methanol, and then solvent was evaporated to afford 31 (297 mg, 98%) as a yellow solid. LRMS (ESI): calc. 314.0; found 315.1 (MH)+.

Provenance & Evidence