反应详情

A mixture of 189 (416.2 mg, 1.152 mmol) and 10% Pd/C (300 mg) in Methanol (25 mL) was shaken under H2 (50 psi) for 18 h at room temperature. The catalyst was filtered through Celite and the filtrate was taken to dryness to give 190 (349 mg, 1.05 mmol, 91% yield) as an orange oil. LRMS (ESI): calc. 333.2, found 334.2 (MH)+.

1. filtrationThe catalyst was filtered through Celite