Acetaldehyde → HCID 24769777, compound

HRID 2196613Notes

Reaction equation

[NH:1]1[CH2:4][CH:3]([O:5][C:6]2[CH:11]=[CH:10][C:9]([S:12][C:13]3[C:14]([C:26]([NH:28][C:29]4[S:33][N:32]=[C:31]([CH3:34])[N:30]=4)=[O:27])=[N:15][C:16]([S:19][C:20]4[N:24]([CH3:25])[CH:23]=[N:22][N:21]=4)=[CH:17][CH:18]=3)=[CH:8][CH:7]=2)[CH2:2]1.[CH:35](=O)[CH3:36]>>[CH2:35]([N:1]1[CH2:2][CH:3]([O:5][C:6]2[CH:11]=[CH:10][C:9]([S:12][C:13]3[C:14]([C:26]([NH:28][C:29]4[S:33][N:32]=[C:31]([CH3:34])[N:30]=4)=[O:27])=[N:15][C:16]([S:19][C:20]4[N:24]([CH3:25])[CH:23]=[N:22][N:21]=4)=[CH:17][CH:18]=3)=[CH:8][CH:7]=2)[CH2:4]1)[CH3:36]

Participants

Reactant 2

HCID 177Acetaldehyde

HCID 69050567HCID 69050567, compound

Product 1

HCID 24769777HCID 24769777, compound

Procedure

Starting from 3-{[4-(azetidin-3-yloxy)phenyl]thio}-N-(3-methyl-1,2,4-thiadiazol-5-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)thio]pyridine-2-carboxamide obtained in Example 2 (step 2) and using acetaldehyde, the entitled compound was obtained as a yellow solid in the same method as in Example 2 (step 3) or in accordance with the method or by combining it with an ordinary method.

Workup

customthe entitled compound was obtained as a yellow solid in the same method as in Example 2 (step 3) or in accordance with the method

Sources & evidence

ORD record: ord-9dd453e0a8b942be91864b22c6b427df
Source dataset: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08338460B2

Reaction notes

Loading…