HCID 44223177, compound → HCID 67155679, compound

Participants

Reaction Steps

2,6-Difluoro-N-(2-(3-hydroxypropyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-3-(propylsulfonamido)benzamide was prepared according to the general procedure of Example 95 substituting 2,6-difluoro-N-(2-(3-hydroxyprop-1-ynyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-3-(propylsulfonamido)benzamide for N-(2-(3-(dimethylamino)prop-1-ynyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-2,6-difluoro-3-(propylsulfonamido)benzamide. 1H NMR (400 MHz, CD3OD) δ 8.28-8.21 (m, 2H), 7.67-7.61 (m, 1H), 7.15-7.09 (m, 1H), 6.24 (s, 1H), 3.66-3.62 (m, 2H), 3.13-3.09 (m, 2H), 2.90-2.85 (m, 2H), 2.01-1.84 (m, 2H), 1.08-1.03 (m, 3H); m/z (APCI-pos) M+1=453.1.

Provenance & Evidence