HCID 67155817, compound → HCID 67155722, compound

Participants

Reaction Steps

N-(2-Cyano-1H-pyrrolo[2,3-b]pyridin-5-yl)-2,6-difluoro-3-(propylsulfonamido)benzamide was prepared following Example 17 substituting 2,6-difluoro-N-(2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-3-(propylsulfonamido)benzamide for 2,6-difluoro-N-(3-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-3-(propylsulfonamido)benzamide. 1H NMR (400 MHz, d6-DMSO) δ 12.98 (br s, 1H), 11.08 (s, 1H), 9.80 (br s, 1H), 8.60 (s, 2H), 7.59-7.52 (m, 1H), 7.43 (s, 1H), 7.30-7.24 (m, 1H), 3.15-3.09 (m, 2H), 1.80-1.73 (m, 2H), 1.02-0.97 (m, 3H); m/z (APCI-neg) M−1=418.1.

Provenance & Evidence