Ethyl Acetate → HCID 67155710, compound

Participants

Reaction Conditions

Reaction Steps

Potassium carbonate (0.306 g, 2.22 mmol) was added to a solution of 2-(methoxymethyl)-5-nitro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (0.11 g, 0.317 mmol) in methanol (3.3 mL) and water (0.9 mL). The reaction mixture was heated at 60° C. for 90 minutes. The reaction mixture was then cooled down. The mixture was treated with water and ethyl acetate, and the layers were separated. The organic layers were washed twice with water, dried over sodium sulfate, filtered, and evaporated to afford 2-(methoxymethyl)-5-nitro-1H-pyrrolo[2,3-b]pyridine (70 mg, quantitative yield).

Provenance & Evidence