反应详情

温度

80 °C

A mixture of 2-iodobenzyl alcohol (11.0 g), 4-chlorophenylbenzeneboronic acid (8.5 g), and [1,1′-bis(diphenylphosphino)ferrocene]dichloropalladium(II) (800 mg) in Na2CO3 (2M solution, 94 mL) and dioxane (300 mL) was heated to 80° C. for 24 hours. The mixture was cooled, the layers were separated, and the organic layer was condensed. The resulting residue was purified by silica gel chromatography eluting with 20% ethyl acetate in hexanes to give the desired product.

1. temperatureThe mixture was cooled
2. customthe layers were separated
3. customcondensed
4. customThe resulting residue was purified by silica gel chromatography
5. washeluting with 20% ethyl acetate in hexanes