HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → HCID 67540398, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | HCID 67540404 | HCID 67540404 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 67540398 | HCID 67540398 | — |
Reaction Steps
A solution of EXAMPLE 44D (500 mg) and piperazine (420 mg) in dimethylsulfoxide (9 ml) was heated at 100° C. for 3 hours. The crude product was isolated by concentration and, following an aqueous work up, was purified on silica gel, and was eluted with a 5, 10% methanol in methylene chloride step gradient.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338466B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-6b716c9a9de04c26b59f443896967f31 |
| Source note | uspto-grants-2012_12 |