Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | N-(6-Nitro-1-oxo-indan-5-yl)-acetamide | HCID 15084115 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 5-Amino-6-nitro-1-indanone | HCID 15084116 | 97.9% |
Reaction Steps
A suspension of N-(6-nitro-1-oxo-indan-5-yl)-acetamide (10 g, 0.042 mol) in HCl (200 ml, 2 N)) and EtOH (100 ml) was refluxed for 30 min. The reaction was cooled to 15° C. and the resulting precipitate was isolated and recrystallized from dilute ethanol to give 7.9 g (97.5%) of yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08338487B2 |
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| Source dataset | uspto-grants-2012_12 |
|---|
| ORD ID | ord-c953a599c6cb4de6a6b3a459794a395f |
|---|
| Source note | uspto-grants-2012_12 |
|---|
