HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86232756, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 15-Crown-5 | HCID 36336 | — |
| Reactant | 2-methyl-1H-pyrrole-3-carbaldehyde | HCID 5324585 | — |
| Reactant | Pyridine-3-sulfonyl chloride hydrochloride | HCID 12571517 | — |
| Product | HCID 86232756 | HCID 86232756 | — |
Reaction Steps
By a similar reaction as in Reference Example 44 and using 2-methyl-1H-pyrrole-3-carbaldehyde (1.10 g), sodium hydride (60% in oil, 1.20 g), 15-crown-5 (6.0 mL) and pyridin-3-ylsulfonyl chloride hydrochloride (3.22 g), the title compound was obtained as white crystals (yield 1.10 g, 44%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338461B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-51742964f6c24fae9ef0b3f957608b9f |
| Source note | uspto-grants-2012_12 |