HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 66974702, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2-Fluoropyridine-3-boronic acid | HCID 2783270 | — |
| Reactant | HCID 66974527 | HCID 66974527 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Product | HCID 66974702 | HCID 66974702 | — |
Reaction Steps
By a similar operation as in Reference Example 79 and using tert-butyl({5-bromo-1-[(6-methoxypyridin-3-yl)sulfonyl]-1H-pyrrol-3-yl}methyl)methylcarbamate (463 mg), (2-fluoropyridin-3-yl)boronic acid (172 mg), sodium carbonate (260 mg) and tetrakis(triphenylphosphine)palladium (176 mg), the title compound was obtained as a pale-yellow oil (yield 293 mg, 45%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338461B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-3d82c7e207e845b9a58cf6350dd0e764 |
| Source note | uspto-grants-2012_12 |