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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2197287Generated: October 31, 2026

Acetyl chloride → HCID 44159533, compound

https://huagongshe.com/reaction/2197287

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
ReactantCyclobutylamineHCID 75645—
Reactant(2'-Formyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 86633167—
ProductHCID 44159533HCID 44159533—

Reaction Steps

{2′-[(Acetyl-cyclobutyl-amino)-methyl]-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl}-acetic acid (Compound 1-30) was prepared according to the procedures outlined in Example 1 by using the following materials: (2′-formyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester, cyclobutylamine and acetyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08338484B2
Source datasetuspto-grants-2012_12
ORD IDord-c63dac4c728c4be7802b17c046fd2844
Source noteuspto-grants-2012_12