HRID2197384

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)Cc1ccc(OC)c(B2OC(C)(C)C(C)(C)O2)c1

HCID58120060

[4-Methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]acetic acid ethyl ester

C17H25BO5

结构：CCN(Cc1cc(C(C)(C)O)ccc1Br)C(=O)OCc1ccccc1

HCID58149231

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(C)(C)O)cc2CN(CC)C(=O)OCc2ccccc2)c1

HCID58149060

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: [2-bromo-5-(1-hydroxy-1-methyl-ethyl)-benzyl]-ethyl-carbamic acid benzyl ester and [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b65475c6619c4689b6b32d584750f886
来源数据集: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08338484B2
来源说明: uspto-grants-2012_12

反应 SMILES

[CH2:1]([O:8][C:9](=[O:25])[N:10]([CH2:13][C:14]1[CH:19]=[C:18]([C:20]([OH:23])([CH3:22])[CH3:21])[CH:17]=[CH:16][C:15]=1Br)[CH2:11][CH3:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:26]([O:28][C:29](=[O:48])[CH2:30][C:31]1[CH:36]=[CH:35][C:34]([O:37][CH3:38])=[C:33](B2OC(C)(C)C(C)(C)O2)[CH:32]=1)[CH3:27]>>[CH2:26]([O:28][C:29](=[O:48])[CH2:30][C:31]1[CH:32]=[C:33]([C:15]2[CH:16]=[CH:17][C:18]([C:20]([OH:23])([CH3:22])[CH3:21])=[CH:19][C:14]=2[CH2:13][N:10]([C:9]([O:8][CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[O:25])[CH2:11][CH3:12])[C:34]([O:37][CH3:38])=[CH:35][CH:36]=1)[CH3:27]