HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(6-bromo-8-phenylimidazo[1,2-a]pyridin-2-yl)acetate → Methyl 2-(6-(5-(isopropylamino)thiazol-2-yl)-8-phenylimidazo[1,2-a]pyridin-2-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(6-bromo-8-phenylimidazo[1,2-a]pyridin-2-yl)acetate | HCID 58207940 | — |
| Reactant | Tert-butyl isopropyl(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)carbamate | HCID 58688452 | — |
| Product | Methyl 2-(6-(5-(isopropylamino)thiazol-2-yl)-8-phenylimidazo[1,2-a]pyridin-2-yl)acetate | HCID 58207962 | — |
Reaction Steps
Prepared in an similar fashion as Example 34, step #4 from tert-butyl isopropyl(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)carbamate and Methyl 2-(6-bromo-8-phenylimidazo[1,2-a]pyridin-2-yl)acetate. LCMS 407.4, HPLC Tr 2.02 min (Conditions C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338604B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-b7969f992e474edcad46e594a433ea6e |
| Source note | uspto-grants-2012_12 |