N-bromobutanimide → HCID 58207875, compound

Participants

Reaction Steps

To a solution of 2-(isopropylthio)thiazole (260 mg, 1.63 mmol) in DMF (2 mL) was added N-bromosuccinimide (435.8 mg, 2.45 mmol). The mixture was stirred at room temperature for 3 hours then subjected to flash column chromatography using 10% ethyl acetate/hexane to give a yellow oil (390 mg, 100% yield). LCMS (Conditions C): Tr 3.67 min.; (M+H)': 237.86 (30%), 239.86 (30%), 195.86 (100%), 197.86 (100%).

Provenance & Evidence