HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2197665Erstellt: 25. Oktober 2026
methyl-(S)-4-(1-carbamoylpropylamino)butyrate → Levetiracetam
https://huagongshe.com/reaction/2197665
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | methyl-(S)-4-(1-carbamoylpropylamino)butyrate | HCID 57424277 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | Levetiracetam | HCID 5284583 | — |
Reaktionsschritte
To the crude methyl-(S)-4-(1-carbamoylpropylamino)butyrate (VIg) in toluene (25 ml) is added hydroxypyrridine (0.7 g, 30 mol %). The mixture is heated to 92° C. until complete conversion. After 17 hours the mixture is concentrated to dryness to yield (S)-2-(2-oxopyrrolidin-1-yl)butyramide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US08338621B2 |
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| Quelldatensatz | uspto-grants-2012_12 |
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| ORD ID | ord-35ad66a7b70145298ece2ce43a329ddb |
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| Quellennotiz | uspto-grants-2012_12 |
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