HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl 2-((6-propylpyridin-2-ylamino)methylene)malonate → 4-Oxo-7-propyl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl 2-((6-propylpyridin-2-ylamino)methylene)malonate | HCID 68461848 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | 4-Oxo-7-propyl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester | HCID 44140174 | 81.1% |
Reaction Steps
The product of Example 2d (6.87 g, 22.4 mmol) was heated in diphenyl ether following the procedure in Example 1b giving the title compound as a tan solid (4.73 g, 81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338605B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-8627ad9a30e749ceab1105fc082b9a2f |
| Source note | uspto-grants-2012_12 |