Sodium Hydroxide → HCID 178438802, compound

HRID 2197700Notes

Reaction equation

HRID 2197700 reaction equation
C(OC([C:6]1[C:15](=[O:16])[C:14]2[C:9](=[N:10][C:11]([CH2:17][CH2:18][CH3:19])=[CH:12][CH:13]=2)[NH:8][CH:7]=1)=O)C.[OH-].[Na+]>>[CH2:17]([C:11]1[N:10]=[C:9]2[C:14]([C:15]([OH:16])=[CH:6][CH:7]=[N:8]2)=[CH:13][CH:12]=1)[CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 441401744-Oxo-7-propyl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester

Product 1

HCID 178438802HCID 178438802, compoundYield 100.4%

Procedure

The product from Example 2e (4.73 g, 18.1 mmol) was reacted with NaOH (756 mg, 18.9 mmol) following the procedure from Example 1c giving the title compound as a solid (3.42 g, 100%).

Sources & evidence

ORD record
ord-f4bb2d0b46554573915e15eb64830f0f
Source dataset
uspto-grants-2012_12
Patent number
US08338605B2

Reaction notes

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