Sodium Hydroxide → HCID 178435554, compound

HRID 2197707Notes

Reaction equation

HRID 2197707 reaction equation
C(OC([C:6]1[C:15](=[O:16])[C:14]2[C:9](=[N:10][C:11]([CH2:17][CH3:18])=[CH:12][CH:13]=2)[NH:8][CH:7]=1)=O)C.[OH-].[Na+]>>[CH2:17]([C:11]1[N:10]=[C:9]2[C:14]([C:15]([OH:16])=[CH:6][CH:7]=[N:8]2)=[CH:13][CH:12]=1)[CH3:18]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 12354420Ethyl 7-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate

Product 1

HCID 178435554HCID 178435554, compoundYield 73%

Procedure

The product from Example 3d (4.70 g, 19.1 mmol) was reacted with NaOH (0.808 g, 20.2 mmol) following the procedure of Example 1c giving the title compound as a light green solid (2.43 g, 73%).

Sources & evidence

ORD record
ord-7901ffb0f1e94ce4ac6faa2560cfdf61
Source dataset
uspto-grants-2012_12
Patent number
US08338605B2

Reaction notes

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