HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-3-nitroanisole → 4-Methoxy-2-nitro-1-phenylsulfanyl-benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-3-nitroanisole | HCID 25140 | — |
| Reactant | Sodium benzenethiolate | HCID 4110039 | — |
| Product | 4-Methoxy-2-nitro-1-phenylsulfanyl-benzene | HCID 68457834 | — |
Reaction Steps
A solution of 1-Chloro-4-methoxy-2-nitro-benzene (3.75 g, 20.0 mmol) was reacted with sodium thiophenolate (3.96 g, 30.0 mmol) at 70° C. for 48 h following the procedure in Example 1e giving the title compound as a yellow oil after silica gel column chromatography eluting with 25% EtOAc/hexane (2.70 g, 54%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338605B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-fd7a79b31a8e469c8ae53150bb673555 |
| Source note | uspto-grants-2012_12 |