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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2197747Generated: November 1, 2026

Ammonium Chloride → N-[4-(2-Amino-4-methyl-phenylsulfanyl)-3-fluoro-phenyl]-acetamide

https://huagongshe.com/reaction/2197747

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium ChlorideHCID 25517—
ReactantN-[3-Fluoro-4-(4-methyl-2-nitro-phenylsulfanyl)-phenyl]-acetamideHCID 68460909—
CatalystIronHCID 23925—
ProductN-[4-(2-Amino-4-methyl-phenylsulfanyl)-3-fluoro-phenyl]-acetamideHCID 68459226—

Reaction Steps

The product from Example 39d was reduced with Fe and NH4Cl following the procedure from Example 237E to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08338605B2
Source datasetuspto-grants-2012_12
ORD IDord-0b1789fe74a34796a628d5f62edf3060
Source noteuspto-grants-2012_12