HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-3-nitrotoluene → HCID 10353762, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-3-nitrotoluene | HCID 6976 | — |
| Reactant | Sodium Phenoxide Trihydrate | HCID 23681143 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 10353762 | HCID 10353762 | — |
Reaction Steps
A solution of sodium phenoxide trihydrate (5.0 g, 30 mmol) and 4-chloro-3-nitrotoluene (2.65 mL, 30 mmol) was heated in 60 mL of DMF at 100° C. for 5 days with stirring following the procedure from Example 1c. The product was purified by silica gel column chromatography eluting with CH2Cl2 giving the title compound as an orange solid (1.36 g, 30%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338605B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-389a3850f3c44c5d9e068b57ddf3f966 |
| Source note | uspto-grants-2012_12 |