Stannous Chloride → 2-(4-Methoxy-phenylsulfanyl)-5-methyl-phenylamine

HRID 2197771Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9][C:10]2[CH:15]=[CH:14][C:13]([CH3:16])=[CH:12][C:11]=2[N+:17]([O-])=O)=[CH:5][CH:4]=1.Cl[Sn]Cl>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([S:9][C:10]2[CH:15]=[CH:14][C:13]([CH3:16])=[CH:12][C:11]=2[NH2:17])=[CH:7][CH:8]=1

Participants

Reactant 2

HCID 24479Stannous Chloride

HCID 602047921-(4-Methoxy-phenylsulfanyl)-4-methyl-2-nitro-benzene

Product 1

HCID 433496162-(4-Methoxy-phenylsulfanyl)-5-methyl-phenylamine

Procedure

The product from Example 50a was reduced with SnCl2 following the procedure from Example 1f giving the title compound.

Sources & evidence

ORD record: ord-f94424848a294907bfd558e043cad9e3
Source dataset: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08338605B2

Reaction notes

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