HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → N-[3-(4-Methyl-2-nitro-phenylsulfanyl)-phenyl]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 3-(4-Methyl-2-nitro-phenylsulfanyl)-phenylamine | HCID 68457917 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[3-(4-Methyl-2-nitro-phenylsulfanyl)-phenyl]-acetamide | HCID 68459008 | 91.3% |
Reaction Steps
The product from Example 71a (650 mg, 2.50 mmol) was dissolved in DCM and acetyl chloride (196 mg, 2.50 mmol) was added. Allowed to stir at room temperature for 1 h, at which time a solid was collected by filtration providing the title compound (690 mg, 61%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338605B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-c2cf9e3e33ed42098db81a986eadde3a |
| Source note | uspto-grants-2012_12 |