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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2197882Generated: October 30, 2026

Benzyl Bromide → 5-Benzyloxy-2-chloro-nitrobenzene

https://huagongshe.com/reaction/2197882

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
Reactant4-Chloro-3-nitrophenolHCID 69127—
Product5-Benzyloxy-2-chloro-nitrobenzeneHCID 11043622—

Reaction Steps

A solution of 4-chloro-3-nitro-phenol was reacted with Bromomethyl-benzene using the conditions described in Example 237C to provide 4-benzyloxy-1-chloro-2-nitro-benzene which was treated sequentially using the procedures from Examples 237D and 237E to provide 4-(2-amino-4-benzyloxy-phenylsulfanyl)-phenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08338605B2
Source datasetuspto-grants-2012_12
ORD IDord-a382311b819547148a3c87076b5a50e2
Source noteuspto-grants-2012_12