Stannous Chloride → 3-(2-Amino-4-chloro-phenoxy)-N,N-dimethyl-benzamide

HRID 2197907Notes

Reaction equation

HRID 2197907 reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:15]=[CH:16][CH:17]=2)[C:10]([N:12]([CH3:14])[CH3:13])=[O:11])=[C:4]([N+:20]([O-])=O)[CH:3]=1.Cl[Sn]Cl>>[NH2:20][C:4]1[CH:3]=[C:2]([Cl:1])[CH:19]=[CH:18][C:5]=1[O:6][C:7]1[CH:8]=[C:9]([CH:15]=[CH:16][CH:17]=1)[C:10]([N:12]([CH3:13])[CH3:14])=[O:11]

Participants

3

Reactant 2

HCID 24479Stannous ChlorideHCID 684583013-(4-Chloro-2-nitro-phenoxy)-N,N-dimethyl-benzamide

Product 1

HCID 684592683-(2-Amino-4-chloro-phenoxy)-N,N-dimethyl-benzamideYield 68%

Procedure

The product from Example 168c (1.5 g, 4.6 mmol) was reacted with SnCl2 as described in Example 1f to give the title compound (0.91 g, 68%).

Sources & evidence

ORD record
ord-60da5bd71768436e9acd887d756b0693
Source dataset
uspto-grants-2012_12
Patent number
US08338605B2

Reaction notes

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