Stannous Chloride → HCID 68459635, compound

HRID 2197913Notes

Reaction equation

HRID 2197913 reaction equation
[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:13]([OH:15])[CH3:14])[CH:10]=[CH:11][CH:12]=2)=[C:4]([N+:18]([O-])=O)[CH:3]=1.Cl[Sn]Cl>>[NH2:18][C:4]1[CH:3]=[C:2]([Cl:1])[CH:17]=[CH:16][C:5]=1[O:6][C:7]1[CH:8]=[C:9]([CH:13]([OH:15])[CH3:14])[CH:10]=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 24479Stannous ChlorideHCID 68458743HCID 68458743, compound

Product 1

HCID 68459635HCID 68459635, compoundYield 70.1%

Procedure

The product from Example 170b (0.98 g, 3.3 mmol) was reduced with SnCl2 as described in Example 1f to give the title compound (0.61 g, 70%).

Sources & evidence

ORD record
ord-0568549c1f21400e914eb736ca3f8068
Source dataset
uspto-grants-2012_12
Patent number
US08338605B2

Reaction notes

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