Stannous Chloride → HCID 26189305, compound

HRID 2197963Notes

Reaction equation

HRID 2197963 reaction equation
[CH3:1][O:2][C:3](=[O:21])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=2[N+:18]([O-])=O)[CH:5]=1.Cl[Sn]Cl>>[CH3:1][O:2][C:3](=[O:21])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=2[NH2:18])[CH:5]=1

Participants

3

Reactant 2

HCID 24479Stannous ChlorideHCID 9112126HCID 9112126, compound

Product 1

HCID 26189305HCID 26189305, compoundYield 95.4%

Procedure

The product from Example 208a (7.20 g, 23.40 mmol) was reduced with SnCl2 (13.310 g, 70.20 mmol) following the procedure from Example 1f to give the title compound (6.2 g, 95%).

Sources & evidence

ORD record
ord-f378b0a48fcb4410bca2b0445325b6af
Source dataset
uspto-grants-2012_12
Patent number
US08338605B2

Reaction notes

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