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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2197964Generated: October 31, 2026

5-Chloro-2-methyl-1,8-naphthyridine → HCID 68460633, compound

https://huagongshe.com/reaction/2197964

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-2-methyl-1,8-naphthyridineHCID 12266372—
ReactantHCID 26189305HCID 26189305—
SolventEthanolHCID 702—
ProductHCID 68460633HCID 68460633—

Reaction Conditions

Temperature80 °C

Reaction Steps

The product from Example 1d (175 mg, 0.979 mmol) and the product from Example 208b (272 mg, 0.979 mmol) were dissolved in 2 mL of abs EtOH and heated to 80° C. for 16 hrs. At this time the reaction mixture was cooled and solvent removed yielding the title compound as a brown foam that was taken forward without purification (410 mg, 93%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08338605B2
Source datasetuspto-grants-2012_12
ORD IDord-4ad6fd7d79474de7b3deb290e4bf4389
Source noteuspto-grants-2012_12