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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2198Generated: October 25, 2026

Benzene → 5-Chloro-1,3-dihydro-3,3-diphenylindol-2-one

https://huagongshe.com/reaction/2198

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneHCID 241—
Reactant5-chloro-1H-indole-2,3-dioneHCID 87203—
ReactantAluminum(III) ChlorideHCID 6451240—
Product5-Chloro-1,3-dihydro-3,3-diphenylindol-2-oneHCID 10758003—

Reaction Steps

This compound is prepared by the method described in Helv. Chim. Acta, 1946, 29, 415-431, by the reaction of benzene with 5-chloroisatin in the presence of aluminum chloride. M.p.=281° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05728723
Source datasetuspto-grants-1998_03
ORD IDord-6ff5774731954061858d03160b92b6f9
Source noteuspto-grants-1998_03