HuagongsheHuagongshe Chemistry Print Report · For research reference only
10-Mercaptomethyl-3-t-butoxycarbonylmethyl-2-oxo-1-azacyclodecane → 10-Mercaptomethyl-2-oxo-1-azacyclodecane-3-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 10-Mercaptomethyl-3-t-butoxycarbonylmethyl-2-oxo-1-azacyclodecane | HCID 19930807 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 10-Mercaptomethyl-2-oxo-1-azacyclodecane-3-acetic acid | HCID 19930854 | — |
Reaction Steps
10-Mercaptomethyl-3-t-butoxycarbonylmethyl-2-oxo-1-azacyclodecane (0.21 g, 0.69 mmol) is dissolved in methylene chloride (15 mL). Gaseous hydrogen chloride is bubbled through the solvent for 15 minutes, and then the reaction is sealed and stirred overnight. The solvent is evaporated the next day to give 10-mercaptomethyl-2-oxo-1-azacyclodecane-3-acetic acid, MS: M+1=260.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05426103 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-46950eaab8e34cc2a47f6fa0233b2643 |
| Source note | uspto-grants-1995_06 |