HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → (R)-methyl 2-amino-3-(tritylthio)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | Fmoc-Cys(Trt)-OMe | HCID 59278482 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (R)-methyl 2-amino-3-(tritylthio)propanoate | HCID 10429690 | — |
Reaction Steps
To a solution of Fmoc-L-Cys(Trt)-OMe (2.58 g, 4.30 mmol) in acetonitrile (20.0 mL) was added diethylamine (20.0 mL). After 30 minutes, the mixture was concentrated in vacuo. The residue was dissolved in acetonitrile (3×10 mL) and concentrated in vacuo to afford L-Cys(Trt)-OMe as crude product which was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08338610B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-0a74ce79f8564bde89c41e528b96b2e4 |
| Source note | uspto-grants-2012_12 |