Hydrochloric Acid → HCID 68795224, compound

Participants

Reaction Steps

To a solution of Example 332A (0.23 g, 0.73 mmol) in ethanol/water (10/2) was added potassium hydroxide (0.2 g, 3.66 mmol). The solution was warmed to 65 degrees for 12 hours, cooled and diluted with ethyl acetate (50 mL). The solution was acidified with 0.5M HCl (10 mL), then washed with brine, dried over MgSO4, filtered, and concentrated to afford the title compound. MS (ESI) m/z 286 (M+H)+.

Provenance & Evidence