(4,4-Dimethoxybutyl)(methyl)amine → 2-(5-chloro-1-(2-(piperidin-1-yl)ethyl)-1H-indol-3-yl)-N-methylethanamine

HRID 2198278Notes

Reaction equation

HRID 2198278 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)N)=[CH:4][CH:3]=1.CO[CH:20](OC)[CH2:21][CH2:22][CH2:23][NH:24][CH3:25]>>[Cl:1][C:2]1[CH:7]=[C:6]2[C:5](=[CH:4][CH:3]=1)[N:8]([CH2:10][CH2:11][N:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)[CH:20]=[C:21]2[CH2:22][CH2:23][NH:24][CH3:25]

Participants

3

Reactant 2

HCID 22563572(4,4-Dimethoxybutyl)(methyl)amineHCID 669116281-(4-Chlorophenyl)-1-(2-(piperidin-1-yl)ethyl)hydrazine

Product 1

HCID 669117682-(5-chloro-1-(2-(piperidin-1-yl)ethyl)-1H-indol-3-yl)-N-methylethanamine

Procedure

The title compound is prepared by General Method 10 using 1-(4-chlorophenyl)-1-(2-(piperidin-1-yl)ethyl)hydrazine (Example 3) and 4,4-dimethoxy-N-methylbutan-1-amine.

Sources & evidence

ORD record
ord-396456d2076d484b8a792d5b8e1af5d6
Source dataset
uspto-grants-2012_12
Patent number
US08338447B2

Reaction notes

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