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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2198492Generated: October 31, 2026

4-Nitroanthranilic acid → HCID 20520133, compound

https://huagongshe.com/reaction/2198492

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Nitroanthranilic acidHCID 12076—
ReactantThionyl ChlorideHCID 24386—
Reactant4-Chloro-8-(trifluoromethyl)quinolineHCID 90262—
Reactant4-Amino-1-methylpiperidineHCID 2737531—
ReactantHCID 20520125HCID 20520125—
ProductHCID 20520133HCID 20520133—

Reaction Steps

4-Nitro-2-(8-trifluoromethyl-4-quinolylamino)benzoyl chloride hydrochloride prepared by the reaction of 4-chloro-8-trifluoromethylquinoline with 2-amino-4-nitrobenzoic acid and treatment of the reaction product with thionyl chloride, is reacted with 4-amino-1-methylpiperidine to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04357333
Source datasetuspto-grants-1982_11
ORD IDord-78830675fff445a0840f5ca0fd8fd08a
Source noteuspto-grants-1982_11