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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2198493Generated: October 25, 2026

3-amino-N-ethylpiperidine → 4-amino-N-(1-ethyl-3-piperidyl)benzamide

https://huagongshe.com/reaction/2198493

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-amino-N-ethylpiperidineHCID 98094—
Reactant4-Aminobenzoyl chloride--hydrogen chloride (1/1)HCID 18688085—
Product4-amino-N-(1-ethyl-3-piperidyl)benzamideHCID 20520143—

Reaction Steps

4-Aminobenzoyl chloride hydrochloride is reacted with 3-amino-1-ethylpiperidine to afford 4-amino-N-(1-ethyl-3-piperidyl)benzamide which is reacted with 4-chloro-8-trifluoromethylquinoline to afford the title compound, melting point 177°-178° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04357333
Source datasetuspto-grants-1982_11
ORD IDord-a594838f3ce64eb8b8f383b693a5db67
Source noteuspto-grants-1982_11