HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 20519106, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethyl 2-bromopropionate | HCID 79040 | — |
| Reactant | HCID 20519112 | HCID 20519112 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 20519106 | HCID 20519106 | — |
Reaction Steps
A mixture of 4-[N-methyl-N-(6-chloro-2-quinoxalinyl)amino]phenol (4 mmole), ethyl 2-bromopropionate (1 ml), potassium carbonate (1.0 g) and butanone (100 ml) was heated under reflux for a period of 12 hr. The solvent was removed by distillation under reduced pressure and the residue was purified by column chromatography over silica gel (eluant dichloromethane/ethanol 98:2) to give ethyl 2-{4-[N-methyl-N-(6-chloro-2-quinoxalinyl)amino]phenoxy}propionate as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04358307 |
| Source dataset | uspto-grants-1982_11 |
| ORD ID | ord-c696bdf8c5524e42bc2e236b859f9d0f |
| Source note | uspto-grants-1982_11 |