HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 13323146, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethyl 2-bromopropionate | HCID 79040 | — |
| Reactant | 4-[(6-Chloro-2-quinoxalinyl)amino]phenol | HCID 136103478 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 13323146 | HCID 13323146 | — |
Reaction Steps
A mixture of 4-[N-(6-chloroquinoxalin-2-yl)amino]phenol (10 mmole), ethyl 2-bromopropionate (10 mmole), anhydrous potassium carbonate (2.0 g) and methyl ethyl ketone (100 ml) was heated under reflux for a period of 12 hours. The mixture was filtered and the solvent was removed by distillation under reduced pressure. The residue was chromatographed over alumina (eluent dichloromethane) to give ethyl 2-{4-[N-(6-chloroquinoxalin-2-yl)amino]phenoxy}propionate, mp 136° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04358307 |
| Source dataset | uspto-grants-1982_11 |
| ORD ID | ord-f4a72b5cd30244ae86dda05ed6d3f30d |
| Source note | uspto-grants-1982_11 |