Potassium Carbonate → HCID 20519103, compound

Participants

Reaction Steps

A mixture of 3-[N-(6-chloroquinoxalin-2-yl)amino]phenol (10 mmole), ethyl 2-bromopropionate (10 mmole), anhydrous potassium carbonate (2 g) and methyl ethyl ketone (100 ml) was heated under reflux for a period of 12 hours. The reaction mixture was filtered and the solvent was removed by distillation under reduced pressure. The residue was purified by chromatography over alumina (eluent dichloromethane) to give ethyl 2-{3-[N-(6-chloroquinoxalin-2-yl)amino]phenoxy}propionate as an oil.

Provenance & Evidence