Hydroxylamine → HCID 72307495, compound

Participants

Reaction Steps

Methyl 4-cyano-2,5-difluorobenzoate (265 mg; 1.34 mmol; 1 eq.) was dissolved in MeOH. Hydroxylamine (0.40 mL; 6.72 mmol; 5 eq.) was added and the mixture was stirred at RT. After one night, the reaction was complete and the solvents were evaporated, affording the title product as a white solid (304 mg; 98%). LC/MS (Method A): 229.0 (M−H)−; 231.0 (M+H)+. HPLC (Method A) Rt 1.08 min (Purity: 98.7%)

Provenance & Evidence