HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 178481328, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 3-(N-Methyl-N-chlorocarbonylamino)-N-methylphthalimide | HCID 117050 | — |
| Reactant | (4-Nitrophenyl)hydrazine | HCID 3310889 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 178481328 | HCID 178481328 | 70.4% |
Reaction Steps
p-Nitrophenylhydrazine (1.5 g, 10 mmole), N-methyl-N-(2-methyl-1,3-dioxoisoindolin-4-yl) carbamoyl chloride (2.5 g, 10 mmole) and 2 ml pyridine were combined in 25 ml dry acetonitrile, heated to reflux, then stirred at room temperature for 4 hours. The solid formed was collected and washed with ether to give 2.6 g of product, m.p. 194°-196° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04358525 |
| Source dataset | uspto-grants-1982_11 |
| ORD ID | ord-1428b4315c51438fa32572add6c41c47 |
| Source note | uspto-grants-1982_11 |