Diethyl Ether → HCID 13071635, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 7.5 g (0.05 mole) of 1,3,4- thiadiazole-2,5-dithiol (DMTD) was stirred in 700 ml of anhydrous ether in a 3-necked round-bottom flask equipped with a thermometer, a reflux condenser, a dropping funnel, and a magnetic stirrer. The solution was maintained at below 25° C. by cooling while 5.9 ml (0.1 mole) of methyl isocyanate and 0.2 ml of triethylamine were added dropwise. The reaction mixture was stirred at 25° C. for 48 hours. The yellow-solid crystals were collected on a filter, washed with ether and dried. The product was 8.2 grams (62 mole % yield) m.p. 162° C., 2,5-bis(N-methylcarbamylthio)-1,3,4-thiadiazole.

Provenance & Evidence