HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → 9-Hydroxymethyl-9,10-dihydro-9,10-methanoanthracene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 9,10-Dihydro-9,10-methanoanthracene-9-carboxaldehyde | HCID 12404141 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | 9-Hydroxymethyl-9,10-dihydro-9,10-methanoanthracene | HCID 13069082 | — |
Reaction Steps
A solution of 9-formyl-9,10-dihydro-9,10-methanoanthracene (200 mg) and sodium borohydride (60 mg) in methanol (5 ml) was stirred at room temperature for 30 minutes. The reaction mixture was diluted with water and extracted with ethyl acetate. The ethyl acetate layer was washed with water, dried over anhydrous sodium sulfate and evaporated to dryness to give 9-hydroxymethyl-9,10-dihydro-9,10-methanoanthracene. M.P. 165°-166° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04358620 |
| Source dataset | uspto-grants-1982_11 |
| ORD ID | ord-b4b5c81661214b2ab17ab7850509a70e |
| Source note | uspto-grants-1982_11 |