反应详情

A solution of 9-aminomethyl-9,10-dihydro-9,10-methanoanthracene (235 mg) and acetic anhydride (217 mg) in ethanol (5.0 ml) was refluxed for 3 hours. The reaction mixture was diluted with water and extracted with ethyl acetate. The ethyl acetate extract was washed with water, aqueous sodium bicarbonate and water, dried over anhydrous sodium sulfate and evaporated to dryness to give 9-acetyl-aminomethyl-9,10-dihydro-9,10-methanoanthracene. M.P. 184°-185.5° C.

1. extractionextracted with ethyl acetate
2. extractionThe ethyl acetate extract
3. washwas washed with water, aqueous sodium bicarbonate and water
4. dry with materialdried over anhydrous sodium sulfate
5. customevaporated to dryness