HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonic Acid → Carnosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonic Acid | HCID 7371 | — |
| Reactant | 1,3-thiazinane-2,4-dione | HCID 2304067 | — |
| Reactant | HCID 22149663 | HCID 22149663 | — |
| Reactant | HCID 178419078 | HCID 178419078 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Carnosine | HCID 439224 | — |
Reaction Steps
Starting with 1.55 g. (10 mmol) of L-histidine, 2.62 g. (20 mmol) of tetrahydro-1,3-thiazin-2,4-dione, 40% methanolic benzyltri-n-butylammonium hydroxide solution to raise the pH benzenesulfonic acid to lower the pH and ethyl acetate as the crystallizing solvent, and following the procedure of Example 1, there is isolated L-carnosine in good yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04359416 |
| Source dataset | uspto-grants-1982_11 |
| ORD ID | ord-3802275f4c724822b4bd6c393c01b762 |
| Source note | uspto-grants-1982_11 |